The directories contain imputed ChIP-seq data from ChromImpute for 449 epigenomes with RNA-seq data only. Each directory correspond to one mark. Files are named based on epigenome without a version ID.

For ChIP-seq the data are in bigwig (.bw) files and correspond to -log10 p-val tracks at a 25 base pair resolution.

To impute with RNA-seq data only using ChromImpute a single signal track was generated based on the RNA-seq data. In the signal track, positions over a gene body were given the value log2(TPM+1) where TPM is the expression of the corresponding gene. This was done at 200bp resolution.  If more than one gene overlapped a position, the gene with the larger first coordinate was used. Positions not overlapping a gene were given a value of 0.

Epigenome IHECRE00000833 had ChIP-seq data that did not pass QC so is included here

Only chr1-22 and chrX were imputed.

checksum_rnaonly.md5 has the checksum values for all the .bw files for all marks.

More information about ChromImpute can be found here:
Ernst J, Kellis M. Large-scale imputation of epigenomic datasets for systematic annotation of diverse human tissues. Nature Biotechnology, 33:364-376, 2015.

Contact Jason Ernst (jason.ernst@ucla.edu) with any questions about the imputed data. Jingyuan Fu contributed to producing these tracks.